Valium Rectal Gel
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Uses of Diazepam Rectal Gel.
Valium rectal gel. Diazepam rectal gel should only be administered by caregivers who in the opinion of the prescribing physician 1 are able to distinguish the distinct cluster of seizures andor the events presumed to herald their onset from the patients ordinary seizure activity 2 have been instructed and judged to be competent to administer the treatment rectally 3 understand explicitly which seizure manifestations may or may not be treated with diazepam rectal gel and 4 are able to monitor the. Diazepam is in a class of medications called benzodiazepines. Prefilled Rectal Delivery System. Diazepam rectal for stopping seizures This leaflet is about the use of rectal diazepam to stop seizures.
It is used to treat certain types of seizures. The objective of the present study was to evaluate the stability of diazepam rectal gel Diastat in various conditions of temperature and light exposure as might be found in ambulances. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy Safety How YouTube works Test new features Press Copyright Contact us Creators. It may be given to you for other reasons.
The commonly accepted maximum dose for rectal administration is 10 mg. Owners were instructed to administer diazepam injectable solution 5 mgmL per rectum to their dogs at a dose of 05 mgkg when an initial generalized seizure occurred and when a second or third generalized seizure occurred within 24 hours of the first seizure. Diazepam rectal gel is well absorbed following rectal administration reaching peak plasma concentrations in 15 hours. How should this medicine be used.
DIASTAT diazepam rectal gel is a gel formulation of diazepam intended for rectal administration for certain patients with epilepsy who are already taking antiepileptic medications and who require occasional use of diazepam to control bouts of increased seizure activity. Diazepam rectal tubes contains benzoic acid E210 and sodium benzoate E211 and it may be mildly irritating to the skin and mucous membranes. This medicine comes in a prefilled plastic applicator. Remove the cap from the prefilled applicator before inserting it.
Talk with the doctor. The lowest GoodRx price for the most common version of diazepam gel is around 8521 76 off the average retail price of 35908. Potentially suicidal individuals should not have access to large amounts of diazepam due to the risk of overdosing. To make the applicator easier to insert use the lubricating gel that came with the medicine.
Three lots of Diastat Xcel Pharmaceuticals San Diego CA in various fillsyringe configurations were evaluated. The comparable intravenous dose is 01-03 mgkg maximum 10 mg. The absolute bioavailability of Diazepam rectal gel relative to. See below for a comprehensive list of adverse effects.
Common side effects of Valium include. Diazepam rectal gel rectal delivery system is a non-sterile diazepam gel provided in a prefilled unitdose rectal delivery system. Diazepam rectal gel is used in emergency situations to stop cluster seizures episodes of increased seizure activity in people who are taking other medications to treat epilepsy seizures. If the seizures persist after rectal diazepam intravenous diazepam should be considered at a dose of 01 mgkg.
Oral solution oral tablet. Stay with the patient after administering diazepam rectal gel to check his or her condition as instructed by the doctor. It is used to help control certain kinds of seizures. Administration The time to give rectal diazepam should be individualised for each child.
Diazepam rectal tubes contains propylene glycol and may cause skin irritation. Diazepam rectal gel contains 5 mgmL diazepam propylene glycol ethyl alcohol 10 hydroxypropyl methylcellulose sodium benzoate benzyl alcohol 15 benzoic acid and water. Generic Diastat Acudial DIAZEPAM is a benzodiazepine. This medication is used to treat episodes of increased seizures such as cluster or breakthrough seizures in people who are already taking medications to control their seizures.
Our preliminary studies demonstrated that nasal administration of diazepam is feasible resulting in Cmax and Tmax values that are comparable to diazepam rectal gel Diastat an FDA-approved product for out-of-hospital treatment of seizure emergencies.